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Authors:

Ihab Abumuhor, BS, MT (ASCP)

Ellen Hope Kearns, MS, SH(ASCP)H

Division of Health Sciences, School of Health, California State University Dominguez Hills, Carson, CA

Thrombotic Thrombocytopenic Purpura

Interfering Substances


Many drugs could affect the platelet count. Table 6 lists some of the drugs that reduce platelet counts or impair platelet function.

Table 6: Select group of interfering substances that adversely affect platelet quantity and platelet function
Interfering Substances that Adversely Affect Platelet Quantity Interfering Substances that Affect Platelet Function
Cardiovascular drugs: Digoxin, Quinidine Aspirin
Psychotrophic drugs: Tricyclics Aspartame
Infections: Ampicillin, Cephalosporins Heparin
High blood pressure: Furosmide, Clorthalidone Vitamin E
Heartburn: Ranitidine, Zantac, Pepcid Garlic/onions
Inflammation / Pain: aspirin, morphine Ginkgo biloba
Seizures: Valproic acid, Phenytoin Grape juice, red wine, raisins
Tuberculosis: Isoniazid Omega 3 fatty acids
Diabetes: Chlorpropamide Ticlopidine

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Last Update: September 11 2012